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By identifying the specific region of growth hormone responsible for lipolytic activity (amino acids 176-191) and isolating this fragment, scientists created a targeted intervention with improved safety profile, fewer contraindications, reduced side effects, and simpler monitoring requirements compared to full growth hormone

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The tumor-bearing mice were intravenously administered Cy7.5-labeled NP4 at a dosage of 2 mg/kg (Ru) once the tumor volume reached approximately 200 mm

TB-500 : Side effects are typically mild and include injection site discomfort, mild lethargy or head rush shortly after administration (due to systemic effect), and, anecdotally, temporary redness or swelling near the injection site