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Studies have also shown that B12 treatment can help to reduce depression symptoms, and even boost weight loss

Long-term carcinogenicity data in rodents is limited

Paul and Brady also note that various single-nucleotide polymorphisms (SNPs) may influence the efficacy and bioavailability, but that at this time there is neither sufficient clinical research in this area nor are tests for these SNPs commercially available

DSIP is injected two to three hours before bed

No studies have shown that extra B12 offers any benefits in these areas

Dosing Schedules That Match the Evidence The schedules below follow the BNF and standard UK haematology guidance