Semaglutide (brand names Wegovy, Ozempic) is a GLP-1 receptor agonist that mimics a hormone that regulates appetite and blood sugar
BPC-157 is a synthetic peptide composed of 15 amino acids, derived from a protein found in gastric juice
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Future investigations should incorporate high-resolution joint-tissue single-cell transcriptomics, long-term OA models, and clinically stratified cohorts to further elucidate the diagnostic utility and mechanistic function of LPCAT3 in OA pathogenesis