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The gut microbiome comes into play here in making sure that the metabolites are excreted and not reabsorbed

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Reduced-form glutathione (2 nmol) was added to the ethanol-soluble fraction of plasma from portal blood

The higher dose (50 mg/kg) showed superior effects, reducing ALT and AST by 74.7% and 70%, respectively, while increasing albumin by 155.6% compared to the TAA group, bringing these parameters closer to normal values (Figures 1AC)