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Despite promising data, TA1 remains experimental for autoimmune conditions

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GRK2 phosphorylates manifold chemokine receptors such as CCR5, CCR2b, CXCR4, and CXCR2, as well as chemotactic receptors for substance P, S1P, and formyl-peptide, which is in charge of leukocyte trafficking to the inflammatory foci, T-cell egression from lymphoid organs, and leukocyte activation and proliferation (33)