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Description

Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A 1 and A 2A adenosine receptors and PI3K, MEK, and PKC pathways

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doi: 10.1158/1078-0432.CCR-13-1787 32 FrankenNARodermondHMStapJHavemanJvan BreeC

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Consequently, the direct regulation of transporters and enzymes within metabolic pathways, as well as the indirect regulation of Gln metabolism through the modulation of associated oncogenes and ncRNAs, may represent promising avenues for future cancer therapies

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