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In animal research, giving Akkermansia to mice improved features of diet-induced metabolic problems (Everard et al., 2013), and a small human trial found that pasteurized Akkermansia was safe, well tolerated, and linked to some improved metabolic markers in adults with overweight or obesity (Depommier et al., 2019)

"The issue is that the skin does not always adapt to this reduction, particularly if there was pre-existing laxity or poor muscle tone

Hansen et al

Mounjaro, which contains the same active ingredient, tirzepatide, is another prescription drug by Eli Lilly that is FDA-approved for type 2 diabetes