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It is designed to be inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption

While many patients tolerate treatment well, understanding potential reactions before beginning therapy helps reduce anxiety and encourages appropriate follow-up if symptoms occur

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10.1016/j.jalz.2011.03.005 [DOI] [PMC free article] [PubMed] [Google Scholar] Packer L

Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity