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In line with patient studies, cellular and mouse models of ALS also showed high levels of ROS, along with elevated oxidation of membrane phospholipids (HNE, MDA), DNA (8-OHdG), and proteins (protein carbonyl groups, 3-NT) [94, 109,110,111]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 463.Lai H.C., Liu T.J., Ting C.T., Yang J.Y., Huang L., Wallace D., et al

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