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By extension, the GHRH-analog Sermorelin should also exert synergistic potential when combined in experiments at the pituitary-cell level

GHK-Cu is 340.4 Da, which sounds permissive, but the practical absorption rate of charged tripeptides through the stratum corneum is essentially zero without enhancement 4

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Wasser, H

Cellular Uptake and Distribution Mechanisms GHK-Cu demonstrates efficient cellular penetration through multiple uptake pathways, including receptor-mediated endocytosis and direct membrane translocation

Such knowledge would not only contribute to a better understanding of the complex biosynthetic pathways involved in the natural generation of depsipeptides, but could also open new avenues for the development of novel pharmaceuticals