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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Diamant M, Nauck MA, Shaginian R, et al

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Curcumin suppresses prostaglandin synthesis and downregulates pro-inflammatory cytokines (interleukin (IL)-1, IL-6, tumor necrosis factor (TNF)-), providing relief in IBD and gastritis

CL Answer Is topical menthol, such as Biofreeze, safe and effective for pain relief