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Placebo-controlled studies are critical here

Progress tracking, including the use of a food diary and self-monitoring, helps maintain momentum

This medication was shown to reduce the risk of CKD progression and renal failure, as well as dialysis initiation, in the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease trial, which involved participants with type 2 diabetes who had albuminuria and advanced CKD

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The rest of us just stumble along the way as best we can