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Symptoms related to folate deficiency include fatigue, apathy, insomnia, impaired concentration, and irritability (30)

(2017) 50:OA3416

The emotional disorders associated with multiple sclerosis

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Upon neuronal depolarization, methylnorepinephrine is released into the synaptic cleft, where it preferentially activates presynaptic 2adrenergic receptors rather than postsynaptic 1receptors ( panel 4 )