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Methods Eligibility criteria The PICOS strategy was defined as follows: P (participants) human subjects, I (interventions) oral LC treatment, C (comparisons) between supplementation and placebo, supplementation and control, or pre- and post- supplementation, O (outcomes) muscle variables, and S (study design) randomized controlled trials, non-randomized controlled trials, non-randomized non-controlled trials
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Semaglutide carries a warning about pancreatitis risk, though serious cases remain rare (less than 0.1% of patients in major trials)
GHK-Cu: Studied for extracellular matrix regulationpromoting collagen/elastin synthesis and tissue remodeling
