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doi: 10.1016/j.jpeds.2011.08.004 59

Neurol Med Chir (Tokyo) (2013) 53:7126

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For pregnant women with dietary deficiency (such as vegans or vegetarians), oral cyanocobalamin at 50-150 micrograms daily is typically recommended, in line with British National Formulary (BNF) guidance

This will require strong evidence from trials that such interventions in asymptomatic or early-stage individuals truly alter the trajectory studies like the Brain-Microbiome project in prodromal AD and the TopHat trial in REM-sleep-behavior-disorder (prodromal PD) are beginning to explore this