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Comparison of Esm1 + ECs in the embryonic villus and postnatal retina As previous work has shown that Esm1 + ECs in the postnatal retina contribute to the expanding arterial network 12,13 , we compared the molecular properties of these cells to the Esm1 + population from embryonic intestine
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Obesity 27 , 917924 (2019)
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Collectively, the synergistic action of AGE-RAGE signaling, metabolic rewiring, and oxidative stress in the DW microenvironment creates a powerful, self-reinforcing circuit that locks macrophages into a persistent M1 state, thereby perpetuating chronic inflammation and impeding the resolution of healing (Figure 3)
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