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The APEX2 substrate 4-(Imidazol-1-yl)phenol (HPI) is oxidized by APEX2 to generate phenoxyl radicals, which further react with luminol to generate luminol radicals

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Sleep deprivation disrupts the lacrimal system and induces dry eye disease

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One of the drugs in the combination known as fen-phen a combination of fenfluramine and phentermine was withdrawn in 1997 for damaging heart valves