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While some individuals may experience modest weight loss during this period, the early phase is generally focused on the body adjusting to the medication

Berberine+ contains a form of berberine (DHB) thats easier for the body to absorb than other forms and is less likely to cause GI discomfort

This is pretty much exactly what we expect from the trials, but it's always nice to have replications and some assurance about the potential viability of using observational data, since it matches at least some of the causal data.There's also similarity to trial side effect profiles: In trials, tirzepatide has fewer and milder side effects while delivering more weight loss

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