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The WHO pharmacological monograph on phentermine identifies this directly as a consequence of its peripheral alpha-agonist activity

While the discovery of rs4149056 in the SLCO1B1 transporter gene is an example of a significant and initially striking finding, several further studies have failed to replicate this finding in different cohorts (Puccetti et al., 2010

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What is the primary mechanism of each compoundand what do you expect the combination to add

Peer-reviewed studies on PT-141 (2003)

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