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Given their substantial fat loss, elevated futile creatine cycling could contribute to thermogenesis during the observed weight loss 50

Laboratory blinding as to case and control status occurred for only one research group [65, 76, 87], although others were blinded to case status but not controls, for example, where the laboratory provided the control data [88, 90, 91] or reference ranges [65, 67, 92, 93] or where another study was used for controls [49, 50]

At the end of this 7-day labelling period ( t = 0 h), samples were collected to verify complete incorporation of the heavy label into cellular proteins

The applications are where the theoretical 5-Amino-1MQ vs MOTS-c debate becomes practical

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