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A mild effect of the intervention was seen on fatigue while a moderate effect was observed on fatigability

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It is the most abundant intracellular antioxidant in human tissues, with the liver serving as both its primary production site and its largest reservoir [5]

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Increasing the glucose concentration from 2.8 to 16.7 mM led to a biphasic stimulation of insulin secretion in pancreases of control mice, an effect that was greatly diminished and delayed in Kcnj11 / mice, while basal insulin secretion (at 2.8 mM glucose) was significantly elevated (Figure 1D)