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A 2019 study in Surgery for Obesity and Related Diseases (Ciangura et al.) tracked menstrual changes in 240 women post-gastric bypass and found 68% reported heavier or irregular periods in months 2 to 6 post-surgery, with normalization by month 9 to 12 as weight loss plateaued

*In a clinical study of 32 women

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Localized injection site reactions are common and usually not dangerous