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Neonatal Opioid Withdrawal Syndrome (NOWS) Advise pregnant women using opioids for an extended period of time of the risk of Neonatal Opioid Withdrawal Syndrome, which may be life-threatening if not recognized and treated

Total time and medical decisionmaking drive code selection

If you're taking insulin or sulfonylureas, discuss glucose monitoring and potential dose adjustments

Other assessment points with better correlation to AUC (especially for once-daily formulations) have been published, i.e., C6 as the most accurate single point or in combination with C2 as a two-point model for AUC0-12 (63) and C2 plus C10 for AUC0-24 (64), but have not yet gained acceptance in clinical practice, mainly due to practical reasons (65)

Symptoms May Appear After a Dose Increase Some people notice new symptoms shortly after increasing their tirzepatide dose