Tone and oxidative stress: Glutathione reduces melanin index and improves brightness in topical and oral trials, with safety confirmed in multi-center reviews
Naringin could accelerate mitochondria-mediated cells apoptosis by generating mitochondrial membrane potential depolarization, by increasing the expression level of Bax, by releasing Cyt c and activating caspase-3 in VK2/E6E7 and End1/E6E7 cells
safer alternatives (oral/topical glutathione, dermatologic/lightening creams or treatments) are preferable
Li Q, Liang J, Fu N, Han Y, Qin J
Glutathione is an important antioxidant that helps protect against oxidative stress
Melanin is the compound in the human body responsible for skin darkness or pigmentation