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The winners of the Lesker Prize will receive 250,000 U.S

Glucagon-like peptide-1 receptors in vagal afferent neurons are required for normal satiation, gastric emptying, and glucose homeostasis

Also known as GGG Tri-agonist, GLP-1/GIP/glucagon tri-agonist, or LY3437943, this injectable medication is similar to existing weight loss medications like tirzepatide and semaglutide but has increased efficacy

clinical trials show cumulative weight loss continues to increase significantly as doses rise from 0.5 mg through 2.4 mg

It also examines the expression of early-response genes in brain regions and the activity of biosynthetic and proteolytic processes

doi: 10.1002/advs.202205462 161 ShouhanWQingchangLXiaodanS