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It often costs time, because the resulting nausea and vomiting can be severe enough to put the entire protocol on hold for weeks

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Unlike fat-soluble vitamins (A, D, E, K), B12 doesnt accumulate to toxic levels from dietary or supplement intake in most circumstances

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Although most of the FRET applications in the early days were related to the estimation of distances between interacting partners, in 1978, Elisa Haas, Ephraim Katchalski-Katzir, and Izchak Z