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doi: 10.1093/humrep/der132

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The basic formula Concentration (mg/mL) = Total peptide (mg) divided by Total water volume (mL) For a 10mg vial: 10mg divided by 1mL = 10mg/mL 10mg divided by 2mL = 5mg/mL 10mg divided by 3mL = 3.33mg/mL 10mg divided by 5mL = 2mg/mL Calculating your draw volume Draw volume (mL) = Desired dose (mg) divided by Concentration (mg/mL) Example: You want a 4mg dose from a vial reconstituted at 5mg/mL

If hot flashes and vasomotor symptoms are primary, we consider transdermal estrogen patches

doi:10.1016/S0021-9258(19)77815-6