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They usually start with high doses and then lower them for maintenance

Peptides are naturally occurring molecules that share a common structure with proteins, as both are composed of amino acids linked together through peptide bonds

Two phase 3 trials of inclisiran in patients with elevated LDL cholesterol

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Peptide bonds are susceptible to cleavage in the presence of water, particularly at elevated temperatures

Studies also indicate its ability to extend the lifespan in animals like rats, mice, and fruit flies