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doi: 10.1186/s12933-023-01765-z

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The gene expression of Gpx4 , one of the most important antioxidant enzymes and the key ferroptosis regulator, is increased in the brain of AD mouse model compared to WT [16]

An increased mitochondrial respiratory activity in the liver therefore speeds up the degradation and prevents the accumulation of fatty acids in the liver, which prevents the development of fibrosis in MASH [15]