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in progress 2assets ClaseprubartDNTH103 / active C1s / long-acting monoclonal antibody / autoimmune / neuromuscular disordersGeneralized Myasthenia Gravis (gMG)Phase IIPhase 2 data reported

This underscores the need for routine monitoring and careful patient selection, particularly in those with metabolic or hepatic comorbidities

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Clinical data from similar medications (semaglutide and tirzepatide) shows an average 70-80% weight regain over 12-18 months after discontinuation, not weeks

With insurance coverage (where available), out-of-pocket costs vary widely from $25 to $500+ per month depending on the plan

The increasing number of affected individuals and families places a heavy burden on the healthcare system(Candon et al., 2018