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Jul 1 2020;105(7)doi:10.1210/clinem/dgaa243

In a study conducted on Adult Wister Rats exposed to cyclophosphamide, the lycopene (given at 0.1 and 0.5 mg/kg) had a preventive impact on the rats bladders according to Jamshidzadeh et al

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The inhibition of system xc - significantly reduces GSH production, thereby decreasing GPX4 activity, leading to lipid ROS build-up and ultimately leading to ferroptosis (44)

A quality check by hierarchical clustering and by plotting of the 2 first principal components confirmed that sample clustering into replicate groups improved after applying the RUVs method with these parameters

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