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Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's progression markers initiative (PPMI): a cross-sectional study

Kraft, V

Endpoints and assessments The primary endpoint was change from baseline in lean body mass at 24 weeks as assessed by whole-body DEXA (Hologic and GE Lunar) scans in participants receiving apitegromab with tirzepatide compared to those receiving tirzepatide alone

Unlike methyl-B12, it does not directly donate methyl groups and can actually help buffer excess methylation

Also, elevated circulating Met levels can be used to predict the risk of developing diabetes