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Isometric force recordings and eccentric (lengthening) contractions (EC) were made on a 300C Muscle Lever (Aurora Scientific Instruments, Canada)

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Interestingly, reduced expression of enzymes involved in FA transport and -oxidation was paralleled by substantial modifications in PPARs, a family of FA-activated nuclear receptors, with attenuated expression of Ppar and Ppar and a dramatic increase in Ppar/ expression in cKOt mice (Supplemental Figure 6)

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