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Among the 85 patients with a repeat lumbar puncture at 6 months, acetazolamide lowered ICP by 112.3 mmH 2 O compared to 52.4 mmH 2 O in the placebo group (27)

The brain stem and cerebellum were removed, and the two remaining hemispheres were homogenized with 1.5 ml ice-cold trichloroacetic acid (50% v/v) in a glass homogenizer

PPAR, PPAR/ and PPAR are the three identified isoforms of PPARs

High proline levels suggest a wider disruption of metabolic processes, often associated with insulin resistance and altered amino acid metabolism 18

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GLP-1 is a hormone that is released in your gut in response to food