Methylation is a controlled transfer of a methyl group (one carbon and three hydrogen atoms) onto proteins, amino acids, enzymes, and DNA in every cell and tissue of the body to regulate healing, cell energy, genetic expression of DNA, liver detoxification, immunity, and neurology
It enhances cell migration and angiogenesis (the formation of new blood vessels), making it key for broader tissue healing
So, for individuals who do not eat meat, obtaining vitamin B12 in bioavailable supplement form is key
for semaglutide, liraglutide and dulaglutide, no dose adjustment is generally required, but monitor in severe renal impairment, especially with gastrointestinal losses Pregnancy and breastfeeding: GLP-1 therapies are not recommended during pregnancy
Patients receiving liraglutide injection in combination with an insulin secretagogue (e.g., sulfonylurea) or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia
Deficiency, which is common and often undiagnosed, presents as fatigue, cognitive fog, mood disruption, and immune vulnerability