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doi: 10.3389/fendo.2025.1568059 Received 28 January 2025 Accepted 10 April 2025 Published 30 April 2025 Volume 16 - 2025 Edited by Joao Dts Anselmo, Hospital do Divino Esprito Santo, Portugal Reviewed by Lucile Butruille, Musum National dHistoire Naturelle, France Updates Copyright 2025 Khudair, Khudair, Niinuma, Habib and Butler

the STEP TEENS trial showed weight rebound after discontinuation (as in adults), suggesting that many patients may need extended or intermittent treatment

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