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Exendin-4 and liraglutide reduced the expression of genes involved in cholesterol synthesis ( ACAT1 , SREBP-2 , HMGCR , and SQLE ), bile acid synthesis ( LXR and CYP7A1 ), and the PCSK9 gene, while increasing the expression of genes associated with the RCT pathway ( ABCA1 and SR-B1 ) and LDL-C uptake ( LDLR )

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