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On the contrary, acylcarnitines of long acyl-chain lengths (C10 to C18) support high mitochondrial respiration in the heart and skeletal muscle, while shorter acylcarnitines (C6 to C8) are oxidized at lower rates
The evolution of GSH in aging fibroblasts showed a sudden increase in its concentration just before cell death, whereas GPx activity was already decreasing at the beginning of passages, and that of glutathione reductase was constant and reaching a very low level at the end of the cell culture, suggesting that the GSH system was probably involved in cell degeneration associated with aging [18]
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(7) Centrifuge for 10 min (12000 rpm, 4C), 150 L of supernatant was loaded into an LC-MS injection vial with a liner tube for LC-MS analysis
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