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Pickart himself made a successful in-vitro (made in test tubes, not on real people) study in 1988 showing that CHK-Cu can stimulate collagen synthesis

Compared to humans and mice, rats have a higher basal level of antioxidant defense gene expression, and rats have a greater capacity to respond to cellular stress, which makes them generally more resistant to drug toxicity [127]

However, no controlled conditions (placebo effects, natural healing, concurrent treatments confound results)

doi: 10.1038/srep37664 (2016)

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