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Medication adjustments might be necessary Sometimes, constipation can be severe enough to warrant adjusting your Ozempic treatment: Slower dose escalation may help staying longer at a lower dose before increasing can give your body more time to adapt Temporary dose reduction might be considered for significant constipation that doesn't respond to other measures Constipation itself usually isnt reason enough to stop Ozempic treatment altogether

10.1172/JCI129188 8 HuisingM

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Notably, several microbial features observed in non-responders overlap with taxa previously associated with greater T2D severity and pro-inflammatory metabolic states (70, 134)