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Long-term administration of salicylate-induced changes in BDNF expression and CREB phosphorylation in the auditory cortex of rats

Its core pathogenesis lies in the synergistic interaction between genetic susceptibility (e.g., gene variants) and environmental triggers (e.g., ultraviolet radiation and gut microbiota dysbiosis), leading to multiple immune system disorders

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The "52-week window" refers to the timeframe of the Hansen et al

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Li B, Goss D, Miller JW