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Alex Dimitriu, MD Medical Reviewer Alex Dimitriu, MD, is dual board-certified in psychiatry and sleep medicine

This triple action creates a powerful combination that affects multiple aspects of metabolism

These symptoms can feel unimportant, making them easy to overlook

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Some report that lower doses, including approaches like low-dose semaglutide or semaglutide microdosing, feel easier to tolerate and less disruptive to daily routines, particularly early in treatment