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IMD-0354 could disrupt the membrane localization of ASCT2 and attenuate mTOR signaling

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As shown by us and others, south Asians and blacks and likely other ethnic groups are more likely to develop type 2 diabetes at lower weight gains than whites across all ages, so that even small population-wide gains in obesity in many countries will lead to large rises in diabetes, Sattar said, adding there was even some trial evidence that drugs that mimic GLP-1 may lower risks of heart disease by almost twice as much in Asian people than in white people

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