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This allows it to remain active in the bloodstream much longer than the bodys own GLP1, which results in more sustained effects

These medicines demonstrated superior tolerability profiles owing to their less impact on gastric emptying, resulting in fewer gastrointestinal side effects

Patients who maintain or build muscle during GLP-1 treatment experience less metabolic slowdown and better weight maintenance after stopping

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Using rodent models of obesity and metabolic dysfunction, the research group demonstrated that the triple-agonist approach produced meaningful reductions in body weight and improved glycaemic parameters compared to both placebo and comparator compounds targeting fewer receptors

The goal is finding the minimum effective dose that keeps weight stable without the full therapeutic load