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Overweight adults (BMI 27) plus at least one weight-related comorbidity (symptomatic heart failure with preserved ejection fraction, noncirrhotic metabolic dysfunction associated with moderate to advanced fibrosis)

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Pretreatment with DZP at a concentration of 18 M effectively reduced the severity of acute PTZ-induced seizures in larvae

Liraglutide leads to treatment discontinuation for adverse effects, with an NNH of 20 (95% CI, 14 to 30)

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