Inflammatory bowel disease, or IBD, is when there is inflammation, or swelling, in the gastrointestinal (GI) tract and a lifelong immune response
Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a vital role in various bodily functions
While oral supplements can help, they often dont absorb as effectivelyespecially for those with digestive issues
When NNMT activity is elevated as documented in obese adipose tissue, several cancer types, and aged skeletal muscle intracellular NAD+ availability decreases, SAM availability decreases, and downstream sirtuin activity (particularly SIRT1 and SIRT3) is reduced
That being said, you should still take vitamin B12 as directed by the information on the leaflet/packet provided with the supplement to ensure you avoid the potential for any unwanted side effects.
But for those noticing a consistent dip in energy or cognitive sharpness, B12 injections could be a game-changer