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Drug interactions warrant consideration during dose escalation

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Choline metabolism underpins macrophage IL-4 polarization and RELMalpha up-regulation in helminth infection

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Serum levels of B-cell-activating factor (BAFF), a cytokine involved in B-cell maturation, are elevated in patients with MASH and correlate with advanced fibrosis (167)

Treatment should be individualized, with clinicians cognizant of possible aesthetic consequences and patients provided both medical and psychosocial support