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Subsequent restriction digest of PCR fragments with ApaI resulted in 141 bp and 516 bp fragments when positive for the F973 modification, whereas nonmodified WT DNA did not contain the ApaI site and thus still showed a 658 bp band upon ApaI digestion
Abbreviations: HbA1c
Symptoms often improve over time but should be monitored closely
Riboflavin is also a co-factor for pyridoxine phosphate oxidase, the enzyme required for vitamin B6 production (as pyridoxal 5-phosphate) which is, in turn, an essential cofactor for the enzymes cystathionine-b-synthase (required for the conversion of homocysteine to cysteine) and cystathionine g-lyase (required for the conversion of cysteine to glutathione)
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King, J
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