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Dehydration can impair cellular function and hinder the bodys ability to produce and utilize glutathione effectively

or swelling anywhere in the body

2.6.4.2 Laboratory 2 TEER was measured using the Millicell Electrical Resistance System-2 meter with an Endohm 12 Tissue Resistance Measurement Chamber electrode (Merck, Darmstadt, Germany)

However, our current understanding of the early implantation events is very limited, mainly because of inaccessibility in vivo as well as lack of appropriate in vitro study models

(PubMed) National Cancer Institute

However, what you tend to feel immediately upon injection is firmness due to swelling and inflammation (think of how a newly-bruised area will feel like a firm bump)