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Jobira et al.(2020) conducted a prospective case-control study demonstrating that obese adolescent PCOS patients exhibit reduced -diversity (Shannon diversity), significantly lower relative abundance of Bacteroidetes , and increased Actinobacteria and Streptococcaceae , all of which closely correlate with testosterone levels and insulin resistance (64)

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This finding further supports the notion that circulating caspase-cleaved CK-18 fragments serve as a valuable diagnostic biomarker for MASH progression

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doi: 10.3389/fimmu.2018.02069 34 ValdiviaA.LyJ.GonzalezL.HussainP.SaingT.IslamogluH.et al

Rare Semaglutide Injection Site Reactions While these reactions are rare, the Mayo Clinic does note them